Abstract
Sugar-peracetylated 1-(β-D-glucopyranosyl)-, 1-(β-D-galactopyranosyl)-, and 1-(β-D-xylopyranosyl)-6-aryl-5-cyano-2-thiouracils 2-4 and the corresponding 1-pyranosyl-2-(pyranosylthio)pyrimidines 5-7 undergo efficient ammonolysis (NH3/MeOH, 0→23°C, 16 h) to give the corresponding 1-(β-D- pyranosyl)-6-aryl-5-cyano-2-thiocytosines.
Original language | English |
---|---|
Pages (from-to) | 4757-4761 |
Number of pages | 5 |
Journal | Tetrahedron Letters |
Volume | 41 |
Issue number | 24 |
DOIs | |
Publication status | Published - Jun 10 2000 |
Externally published | Yes |
Keywords
- 1-(β-D-pyranosyl)-2-thiocytosines
- 6-aryl-5-cyano-2-thiouracils
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry