The first report of familial adult T‐cell leukemia lymphoma in the United States

Srdjan Denic, Jonathan Abramson, Ravi Anandakrishnan, Muthuswamy Krishnamurthy, Harvey Dosik

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Two patients, a daughter and her father, developed the acute type of adult T‐cell leukemia/lymphoma (ATLL) within a 3‐month period. Antibodies against HTLV‐I have been found in both wives of the father. The second wife acquired the infection from her husband within 3 years of marriage. The patients described represent the first cases of familial ATLL in the United States. ATLL continues to be frequently misdiagnosed in the United States. A positive family history consistent with this disease in a patient with a lymphoid malignancy may be a helpful clue for earlier diagnosis.

Original languageEnglish
Pages (from-to)281-283
Number of pages3
JournalAmerican Journal of Hematology
Volume27
Issue number4
DOIs
Publication statusPublished - Apr 1988
Externally publishedYes

Keywords

  • HTLV‐I
  • horizontal transmission
  • vertical transmission

ASJC Scopus subject areas

  • Hematology

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