TY - JOUR
T1 - The first report of familial adult T‐cell leukemia lymphoma in the United States
AU - Denic, Srdjan
AU - Abramson, Jonathan
AU - Anandakrishnan, Ravi
AU - Krishnamurthy, Muthuswamy
AU - Dosik, Harvey
PY - 1988/4
Y1 - 1988/4
N2 - Two patients, a daughter and her father, developed the acute type of adult T‐cell leukemia/lymphoma (ATLL) within a 3‐month period. Antibodies against HTLV‐I have been found in both wives of the father. The second wife acquired the infection from her husband within 3 years of marriage. The patients described represent the first cases of familial ATLL in the United States. ATLL continues to be frequently misdiagnosed in the United States. A positive family history consistent with this disease in a patient with a lymphoid malignancy may be a helpful clue for earlier diagnosis.
AB - Two patients, a daughter and her father, developed the acute type of adult T‐cell leukemia/lymphoma (ATLL) within a 3‐month period. Antibodies against HTLV‐I have been found in both wives of the father. The second wife acquired the infection from her husband within 3 years of marriage. The patients described represent the first cases of familial ATLL in the United States. ATLL continues to be frequently misdiagnosed in the United States. A positive family history consistent with this disease in a patient with a lymphoid malignancy may be a helpful clue for earlier diagnosis.
KW - HTLV‐I
KW - horizontal transmission
KW - vertical transmission
UR - http://www.scopus.com/inward/record.url?scp=0023897810&partnerID=8YFLogxK
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U2 - 10.1002/ajh.2830270410
DO - 10.1002/ajh.2830270410
M3 - Article
C2 - 2895582
AN - SCOPUS:0023897810
SN - 0361-8609
VL - 27
SP - 281
EP - 283
JO - American Journal of Hematology
JF - American Journal of Hematology
IS - 4
ER -