The oncogenic potential of growth hormone

Jo K. Perry; B. Starling Emerald; Hichem C. Mertani; Peter E. Lobie

doi:10.1016/j.ghir.2006.09.006

The oncogenic potential of growth hormone

Jo K. Perry, B. Starling Emerald, Hichem C. Mertani, Peter E. Lobie

Research output: Contribution to journal › Review article › peer-review

123 Citations (Scopus)

Abstract

A growing body of recent literature indicates that in addition to an essential role in growth and development, growth hormone may also play a more sinister role in oncogenic transformation and neoplastic progression. Here we review the accumulating evidence implicating growth hormone in the development and progression of cancer and describe what is known of the mechanisms utilised by this hormone in neoplastic transformation.

Original language	English
Pages (from-to)	277-289
Number of pages	13
Journal	Growth Hormone and IGF Research
Volume	16
Issue number	5-6
DOIs	https://doi.org/10.1016/j.ghir.2006.09.006
Publication status	Published - Oct 2006
Externally published	Yes

Keywords

Growth hormone
Oncogenicity

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology

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10.1016/j.ghir.2006.09.006

Cite this

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title = "The oncogenic potential of growth hormone",

abstract = "A growing body of recent literature indicates that in addition to an essential role in growth and development, growth hormone may also play a more sinister role in oncogenic transformation and neoplastic progression. Here we review the accumulating evidence implicating growth hormone in the development and progression of cancer and describe what is known of the mechanisms utilised by this hormone in neoplastic transformation.",

keywords = "Growth hormone, Oncogenicity",

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year = "2006",

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AU - Emerald, B. Starling

AU - Mertani, Hichem C.

AU - Lobie, Peter E.

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N2 - A growing body of recent literature indicates that in addition to an essential role in growth and development, growth hormone may also play a more sinister role in oncogenic transformation and neoplastic progression. Here we review the accumulating evidence implicating growth hormone in the development and progression of cancer and describe what is known of the mechanisms utilised by this hormone in neoplastic transformation.

AB - A growing body of recent literature indicates that in addition to an essential role in growth and development, growth hormone may also play a more sinister role in oncogenic transformation and neoplastic progression. Here we review the accumulating evidence implicating growth hormone in the development and progression of cancer and describe what is known of the mechanisms utilised by this hormone in neoplastic transformation.

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KW - Oncogenicity

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ER -

The oncogenic potential of growth hormone

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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