The oncogenic potential of growth hormone

Jo K. Perry, B. Starling Emerald, Hichem C. Mertani, Peter E. Lobie

Research output: Contribution to journalReview articlepeer-review

124 Citations (Scopus)


A growing body of recent literature indicates that in addition to an essential role in growth and development, growth hormone may also play a more sinister role in oncogenic transformation and neoplastic progression. Here we review the accumulating evidence implicating growth hormone in the development and progression of cancer and describe what is known of the mechanisms utilised by this hormone in neoplastic transformation.

Original languageEnglish
Pages (from-to)277-289
Number of pages13
JournalGrowth Hormone and IGF Research
Issue number5-6
Publication statusPublished - Oct 2006
Externally publishedYes


  • Growth hormone
  • Oncogenicity

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology


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