Abstract
The cross‐over design for clinical trials when responses are binary is discussed. Three tests which have been proposed for the analysis of this problem are compared by an assessment of their assumptions. A simple test to establish whether it is appropriate to include observations from the second period is presented.
Original language | English |
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Pages (from-to) | 863-869 |
Number of pages | 7 |
Journal | Biometrical Journal |
Volume | 28 |
Issue number | 7 |
DOIs | |
Publication status | Published - 1986 |
Externally published | Yes |
Keywords
- Carry‐over effects
- Clinical trials
- Cross‐over design
- Hypothesis testing
ASJC Scopus subject areas
- Statistics and Probability
- Statistics, Probability and Uncertainty