TY - GEN
T1 - Toxicity assessment of date pit activated carbon nanomaterials in hepatocytes
AU - Mathew, Betty Titus
AU - Raji, Shaima
AU - Mourad, A. H.I.
AU - Al Naqbi, Ali Abdullah Hilal
AU - El-Tarabily, Khaled A.
AU - Amin, Amr
AU - Alnaimat, Fadi
AU - Mathew, Bobby
N1 - Publisher Copyright:
© 2019 IEEE.
PY - 2019/5/14
Y1 - 2019/5/14
N2 - This main objective of this work is to synthesize and characterize activated carbon (AC) produced from date pits and screening of cytotoxicity assay with carbon nanoparticles on hepatocytes namely (THLE2 and Hep G2). The AC was prepared by physical activation method at 900C in a tube furnace. Scanning Electron Microscopy analysis illustrated that the activation has increased the pores intensity. In the biological assays, cytotoxicity test of the THLE2 cells and HepG2 cells showed viability remained closed to 100% when exposed to date pit carbon nanomaterial. Transmission Electron Microscopy (TEM) was conducted to check the apoptosis severity of nanoparticles on the cells. The results showed that the cells regained its capacity even when the particles were ingested by the cells.
AB - This main objective of this work is to synthesize and characterize activated carbon (AC) produced from date pits and screening of cytotoxicity assay with carbon nanoparticles on hepatocytes namely (THLE2 and Hep G2). The AC was prepared by physical activation method at 900C in a tube furnace. Scanning Electron Microscopy analysis illustrated that the activation has increased the pores intensity. In the biological assays, cytotoxicity test of the THLE2 cells and HepG2 cells showed viability remained closed to 100% when exposed to date pit carbon nanomaterial. Transmission Electron Microscopy (TEM) was conducted to check the apoptosis severity of nanoparticles on the cells. The results showed that the cells regained its capacity even when the particles were ingested by the cells.
KW - Cytotoxicity
KW - DLS
KW - Date pit Activated carbon
KW - Hepatocytes
KW - TEM
KW - Zeta-potential
UR - http://www.scopus.com/inward/record.url?scp=85067069707&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85067069707&partnerID=8YFLogxK
U2 - 10.1109/ICASET.2019.8714255
DO - 10.1109/ICASET.2019.8714255
M3 - Conference contribution
AN - SCOPUS:85067069707
T3 - 2019 Advances in Science and Engineering Technology International Conferences, ASET 2019
BT - 2019 Advances in Science and Engineering Technology International Conferences, ASET 2019
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2019 Advances in Science and Engineering Technology International Conferences, ASET 2019
Y2 - 26 March 2019 through 10 April 2019
ER -