Transient diabetes insipidus and hypopituitarism after pituitary apoplexy: A rare association with pericardial effusion and painless thyroiditis

John Punnose, M. M. Agarwal, J. S. Premchandran

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

Pituitary apoplexy in a 38-year-old male patient with acromegaly who presented with pericardial effusion, anterior pituitary dysfunction, and diabetes insipidus is described. With corticosteroid therapy, there was good initial recovery of pituitary function and regression of pericardial effusion. On withdrawal of corticosteroids, he developed painless thyroiditis, with transient thyrotoxicosis. Subsequently, the pituitary function tests remained normal for a year, but later he gradually developed hypogonadotropic hypogonadism, hypocortisolism, growth hormone deficiency, and progressive pituitary atrophy, resulting in empty sella syndrome.

Original languageEnglish
Pages (from-to)261-264
Number of pages4
JournalAmerican Journal of the Medical Sciences
Volume319
Issue number4
DOIs
Publication statusPublished - Apr 2000
Externally publishedYes

Keywords

  • Acromegaly
  • Hypopituitarism
  • Painless thyroiditis
  • Pericardial effusion
  • Pituitary apoplexy

ASJC Scopus subject areas

  • General Medicine

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