Transition dynamics of HIV disease in a cohort of African prostitutes: A Markov model approach

Nico J.D. Nagelkerke; Francis A. Plummer; Donna Holton; Aggrey O. Anzala; Firoze Manji; Elizabeth N. Ngugi; Stephen Moses

Transition dynamics of HIV disease in a cohort of African prostitutes: A Markov model approach

Nico J.D. Nagelkerke, Francis A. Plummer, Donna Holton, Aggrey O. Anzala, Firoze Manji, Elizabeth N. Ngugi, Stephen Moses

Research output: Contribution to journal › Article › peer-review

34 Citations (Scopus)

Abstract

The progression of HIV-related disease from infection to death is represented as a staged Markov model. Transitions between stages are considered reversible. The model is fitted to data from a cohort of African prostitutes by means of maximum likelihood. It appears that the progression to symptomatic disease (Centers for Disease Control stage IV) in this population is considerably more rapid than that reported from studies in Western countries.

Original language	English
Pages (from-to)	743-747
Number of pages	5
Journal	AIDS
Volume	4
Issue number	8
Publication status	Published - Aug 1990
Externally published	Yes

Keywords

Disease stage
Incubation time
Markov model
Prostitutes

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Infectious Diseases

Cite this

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abstract = "The progression of HIV-related disease from infection to death is represented as a staged Markov model. Transitions between stages are considered reversible. The model is fitted to data from a cohort of African prostitutes by means of maximum likelihood. It appears that the progression to symptomatic disease (Centers for Disease Control stage IV) in this population is considerably more rapid than that reported from studies in Western countries.",

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AU - Nagelkerke, Nico J.D.

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AU - Holton, Donna

AU - Anzala, Aggrey O.

AU - Manji, Firoze

AU - Ngugi, Elizabeth N.

AU - Moses, Stephen

PY - 1990/8

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AB - The progression of HIV-related disease from infection to death is represented as a staged Markov model. Transitions between stages are considered reversible. The model is fitted to data from a cohort of African prostitutes by means of maximum likelihood. It appears that the progression to symptomatic disease (Centers for Disease Control stage IV) in this population is considerably more rapid than that reported from studies in Western countries.

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KW - Incubation time

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ER -

Transition dynamics of HIV disease in a cohort of African prostitutes: A Markov model approach

Abstract

Keywords

ASJC Scopus subject areas

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