Treating delusional disorder: A comparison of cognitive-behavioural therapy and attention placebo control

Kieron O'Connor, Emmanuel Stip, Marie Claude Pélissier, Frederick Aardema, Stéphane Guay, Gilles Gaudette, Ian Van Haaster, Sophie Robillard, Sébastien Grenier, Yves Careau, Pascale Doucet, Vicky Leblanc

Research output: Contribution to journalArticlepeer-review

51 Citations (Scopus)


Objective: Cognitive-behavioural therapy (CBT) has proved effective in treating delusions, both in schizophrenia and delusional disorder (DD). Clinical trials of DD have mostly compared CBT with either treatment as usual, no treatment, or a wait-list control. This current study aimed to assess patients with DD who received CBT, compared with an attention placebo control (APC) group. Method: Twenty-four individuals with DD were randomly allocated into either CBT or APC groups for a 24-week treatment period. Patients were diagnosed on the basis of structured clinical interviews for mental disorders and the Maudsley Assessment of Delusion Schedule (MADS). Results: Completers in both groups (n = 11 for CBT; n = 6 for APC) showed clinical improvement on the MADS dimensions of Strength of Conviction, Insight, Preoccupation, Systematization, Affect Relating to Belief, Belief Maintenance Factors, and Idiosyncrasy of Belief. Conclusion: When compared with APC, CBT produced more impact on the MADS dimensions for Affect Relating to Belief, Strength of Conviction, and Positive Actions on Beliefs.

Original languageEnglish
Pages (from-to)182-190
Number of pages9
JournalCanadian Journal of Psychiatry
Issue number3
Publication statusPublished - Mar 2007
Externally publishedYes


  • Attention placebo control
  • Cognitive-behavioural therapy
  • Delusional disorder

ASJC Scopus subject areas

  • Psychiatry and Mental health


Dive into the research topics of 'Treating delusional disorder: A comparison of cognitive-behavioural therapy and attention placebo control'. Together they form a unique fingerprint.

Cite this