TY - JOUR
T1 - Trends in UK regional cancer mortality 1991-2007
AU - Marshall, Dominic C.
AU - Webb, Thomas E.
AU - Hall, Richard A.
AU - Salciccioli, Justin D.
AU - Ali, Raghib
AU - Maruthappu, Mahiben
N1 - Funding Information:
Data source. Cancer mortality data were collected by population-based cancer registries for UK regions (Steliarova-Foucher et al, 2013). Cancer diagnoses were recorded according to the International Classification of Disease (ICD) at the time of death. During the calendar period for this investigation two different revisions of the ICD were used, the 9th revision was used across the United Kingdom until 2001 when the 10th revision was implemented. Mortality data for cancers of interest are available publically through the World Health Organisation and can be abstracted from the EUREG database (http://eco.iarc.fr/eureg/; accessed 09/ 2014) developed by the International Agency for Research on Cancer (IARC) in partnership with the European Network of Cancer Registries. IARC is responsible for data management and maintains data quality through their Check and Conversion program, which includes routine screening with pre-defined algorithms for validity and consistency (Ferlay et al, 2005).
Publisher Copyright:
© 2016 Cancer Research UK.
PY - 2016/2/2
Y1 - 2016/2/2
N2 - Background:Until 1990, there was an upward trend in mortality from breast, lung, prostate, and colon cancers in the United Kingdom. With improvements in cancer treatment there has, in general, been a fall in mortality over the last 20 years. We evaluate regional cancer mortality trends in the United Kingdom between 1991 and 2007.Methods:We analysed mortality trends for breast, lung, prostate, and colon cancers using data obtained from the EUREG cancer database. We have described changes in age-standardised rates (using European standard population) per 100 000 for cancer mortality and generated trends in mortality for the 11 regions using Joinpoint regression.Results:Across all regions in the United Kingdom there was a downward trend in mortality for the four most common cancers in males and females. Overall, deaths from colon cancer decreased most rapidly and deaths from prostate cancer decreased at the slowest rate. Similar downward trends in mortality were observed across all regions of the United Kingdom with the data for lung cancer exhibiting the greatest variation.Conclusions:Mortality from the four most common cancers decreased across all regions of the United Kingdom; however, the rate of decline varied between cancer type and in some instances by region.
AB - Background:Until 1990, there was an upward trend in mortality from breast, lung, prostate, and colon cancers in the United Kingdom. With improvements in cancer treatment there has, in general, been a fall in mortality over the last 20 years. We evaluate regional cancer mortality trends in the United Kingdom between 1991 and 2007.Methods:We analysed mortality trends for breast, lung, prostate, and colon cancers using data obtained from the EUREG cancer database. We have described changes in age-standardised rates (using European standard population) per 100 000 for cancer mortality and generated trends in mortality for the 11 regions using Joinpoint regression.Results:Across all regions in the United Kingdom there was a downward trend in mortality for the four most common cancers in males and females. Overall, deaths from colon cancer decreased most rapidly and deaths from prostate cancer decreased at the slowest rate. Similar downward trends in mortality were observed across all regions of the United Kingdom with the data for lung cancer exhibiting the greatest variation.Conclusions:Mortality from the four most common cancers decreased across all regions of the United Kingdom; however, the rate of decline varied between cancer type and in some instances by region.
KW - cancer
KW - mortality trends
KW - regional variation
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U2 - 10.1038/bjc.2015.428
DO - 10.1038/bjc.2015.428
M3 - Article
C2 - 26766741
AN - SCOPUS:84956780122
SN - 0007-0920
VL - 114
SP - 340
EP - 347
JO - British Journal of Cancer
JF - British Journal of Cancer
IS - 3
ER -