Two ways of preparing benzonitriles using BrCCl3-PPh3 as the reagent

Yosef Al Jasem; Mohamed Barkhad; Mona Al Khazali; Hifsa Pervez Butt; Noha Ashraf El-Khwass; Mariam Al Azani; Bassam Al Hindawi; Thies Thiemann

doi:10.3184/174751914X13891131118347

Two ways of preparing benzonitriles using BrCCl₃-PPh₃ as the reagent

Yosef Al Jasem, Mohamed Barkhad, Mona Al Khazali, Hifsa Pervez Butt, Noha Ashraf El-Khwass, Mariam Al Azani, Bassam Al Hindawi, Thies Thiemann

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Benzamides were converted into benzonitriles with BrCCl₃- PPh₃-Et₃N in CH₂Cl₂ in an Appel-type reaction. Benzaldoximes could be transformed to benzonitriles under identical conditions. It was found that the reaction system BrCCl₃-(2 equiv.)PPh₃ was also suitable for these transformations with PPh ₃ replacing Et₃N.

Original language	English
Pages (from-to)	80-84
Number of pages	5
Journal	Journal of Chemical Research
Volume	38
Issue number	2
DOIs	https://doi.org/10.3184/174751914X13891131118347
Publication status	Published - Feb 2014

Keywords

Appel-type reaction
Benzaldoximes
Benzamides
Benzonitriles
Bromotrichloromethane

ASJC Scopus subject areas

Chemistry(all)

Access to Document

10.3184/174751914X13891131118347

Cite this

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title = "Two ways of preparing benzonitriles using BrCCl3-PPh3 as the reagent",

abstract = "Benzamides were converted into benzonitriles with BrCCl3- PPh3-Et3N in CH2Cl2 in an Appel-type reaction. Benzaldoximes could be transformed to benzonitriles under identical conditions. It was found that the reaction system BrCCl3-(2 equiv.)PPh3 was also suitable for these transformations with PPh 3 replacing Et3N.",

keywords = "Appel-type reaction, Benzaldoximes, Benzamides, Benzonitriles, Bromotrichloromethane",

author = "Jasem, {Yosef Al} and Mohamed Barkhad and Khazali, {Mona Al} and Butt, {Hifsa Pervez} and El-Khwass, {Noha Ashraf} and Azani, {Mariam Al} and Hindawi, {Bassam Al} and Thies Thiemann",

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journal = "Journal of Chemical Research",

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T1 - Two ways of preparing benzonitriles using BrCCl3-PPh3 as the reagent

AU - Jasem, Yosef Al

AU - Barkhad, Mohamed

AU - Khazali, Mona Al

AU - Butt, Hifsa Pervez

AU - El-Khwass, Noha Ashraf

AU - Azani, Mariam Al

AU - Hindawi, Bassam Al

AU - Thiemann, Thies

PY - 2014/2

Y1 - 2014/2

N2 - Benzamides were converted into benzonitriles with BrCCl3- PPh3-Et3N in CH2Cl2 in an Appel-type reaction. Benzaldoximes could be transformed to benzonitriles under identical conditions. It was found that the reaction system BrCCl3-(2 equiv.)PPh3 was also suitable for these transformations with PPh 3 replacing Et3N.

AB - Benzamides were converted into benzonitriles with BrCCl3- PPh3-Et3N in CH2Cl2 in an Appel-type reaction. Benzaldoximes could be transformed to benzonitriles under identical conditions. It was found that the reaction system BrCCl3-(2 equiv.)PPh3 was also suitable for these transformations with PPh 3 replacing Et3N.

KW - Appel-type reaction

KW - Benzaldoximes

KW - Benzamides

KW - Benzonitriles

KW - Bromotrichloromethane

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