Use of genomic information in health impact assessment is yet to come: A systematic review

Balázs Ádám, Szabolcs Lovas, Róza Ádány

Research output: Contribution to journalReview articlepeer-review

Abstract

Information generated by genetic epidemiology and genomics studies has been accumulating at fast pace, and this knowledge opens new vistas in public health, allowing for the understanding of gene–environment interactions. However, the translation of genome-based knowledge and technologies to the practice of healthcare, and especially of public health, is challenging. Because health impact assessment (HIA) proved to be an effective tool to assist consideration of health issues is sectoral policymaking, this study aimed at exploring its role in the translational process by a systematic literature review on the use of genetic information provided by genetic epidemiology and genomics studies in HIA. PubMed, Scopus, and Web of Science electronic databases were searched and the findings systematically reviewed and reported by the PRISMA guidelines. The review found eight studies that met the inclusion criteria, most of them theoretically discussing the use of HIA for introducing genome-based technologies in healthcare practice, and only two articles considered, in short, the possibility for a generic application of genomic information in HIA. The findings indicate that HIA should be more extensively utilized in the translation of genome-based knowledge to public health practice, and the use of genomic information should be facilitated in the HIA process.

Original languageEnglish
Article number9417
Pages (from-to)1-14
Number of pages14
JournalInternational Journal of Environmental Research and Public Health
Volume17
Issue number24
DOIs
Publication statusPublished - Dec 2 2020

Keywords

  • Genetic epidemiology
  • Genomics
  • Health impact assessment
  • Public health
  • Public health genomics
  • Translation

ASJC Scopus subject areas

  • Pollution
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

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