@article{8540a6d57c62475bb1c5b2b7672edb2b,
title = "Visual P300 in treatment-resistant schizophrenic patients",
abstract = "Although cognitive functioning in schizophrenia continues to be the focus of considerable research, few studies have attempted to evaluate the cognitive functions of neuroleptic treatment-resistant schizophrenic patients. Reduced amplitude of the P300 event-related potential (ERP) is one of the most consistently reported cognitive abnormality in schizophrenia. We therefore sought to determine whether treatment-resistant schizophrenic patients are also characterized by a significant reduction in P300 amplitude. Subjects responded to an infrequent visual stimulus while ignoring binaurally presented auditory stimuli. No group differences were observed for reaction time or P300 amplitude. The percentage of correct responses was excellent for all subjects, although controls were more accurate.",
author = "Roth, {Robert M.} and Milovan, {Denise L.} and Jacinthe Baribeau and Emanuel Stip",
note = "Funding Information: This project was supported by grants from FRSQ-Qu{\'e}bec and SANDOZ Pharmaceuticals Canada to E. Stip. Equipment was supported by the Evoked Potentials Laboratory, Fernand Seguin Research Center, Louis H. Lafontaine Hospital. Funding Information: Funding was provided by grants to E. Roy fron NSERC and the Ontario Mental Health Foundation. Funding Information: 13 Supported by an intramural research grant from The National Aviary. The generous assistance offered by the entire staff at the National Aviary is greatly appreciated. The authors thank both Nikki Wright and Katie Brillman for their contributions to this project. Funding Information: Pegboard performance (Annett, 1967) was studied in 32 right-handed individuals while Trunk posture (Straight, Bent) and foot Stance (feet Apart, tandem Romberg position) were manipulated. Movement time (MT) was measured at the time to complete one trial of the 10-peg task. A repeated measures ANOVA yielded significant main effects of Hand (LH > RH, p < .001) and Trunk (Bent > Straight, p < .001). No interactions reached significance (p > .15). MT interference scores were calculated for each hand relative to a sitting control condition. Contrary to a previous study (Westwood et al., in press), there was a nonsignificant trend toward greater interference for the left than right hand in the Bent posture (p> .40). Results are interpreted in terms of the relationship between postural demands and movement control. ª 1999 Academic Press 14 This research was funded in part through grants to E. A. Roy from NSERC and the Ontario Mental Health Foundation.",
year = "1999",
month = jun,
doi = "10.1006/brcg.1998.1068",
language = "English",
volume = "40",
pages = "247--284",
journal = "Brain and Cognition",
issn = "0278-2626",
publisher = "Academic Press Inc.",
number = "1",
}